Publications
Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
JoVE (Journal of Visualized Experiments)
Diana Kuehn, Shoaib Majeed, Emmanuel Guedj, Remi Dulize, Karine Baumer, Anita Iskandar, Stephanie Boue, Florian Martin, Radina Kostadinova, Carole Mathis, Nikolai V. Ivanov, Stefan Frentzel, Julia Hoeng, Manuel C. Peitsch
respiratory epitheliumprotein expressionmetabolismmucilair™gene expressionair liquid interface (ali) culture
Targeted omics analyses, and metabolic enzyme activity assays demonstrate maintenance of key mucociliary characteristics in long term cultures of reconstituted human airway epithelia
Toxicology in Vitro
Andrew Baxter, Simon Thain, Anisha Banerjee, Linsey Haswell, Aleesha Parmar, Gary Phillips, Emmanuel Minet
Engineering an in vitro air-blood barrier by 3D bioprinting
Scientific Reports
Lenke Horváth, Yuki Umehara, Corinne Jud, Fabian Blank, Alke Petri-Fink, Barbara Rothen-Rutishauser
human bronchial epithelial cellscalciumcystic fibrosistrpv6
The low PLC-δ1 expression in cystic fibrosis bronchial epithelial cells induces upregulation of TRPV6 channel activity
Cell Calcium
Laura Vachel, Caroline Norez, Christophe Jayle, Frédéric Becq, Clarisse Vandebrouck
mucociliary clearancemucociliary apparatuscerium oxide3d human bronchial epithelial model
Toxicity assessment of aggregated/agglomerated cerium oxide nanoparticles in an in vitro 3D airway model: The influence of mucociliary clearance
Toxicology in Vitro
C. Frieke Kuper, Mariska Gröllers-Mulderij, Thérèse Maarschalkerweerd, Nicole M. M. Meulendijks, Astrid Reus, Frédérique van Acker, Esther K. Zondervan-van den Beuken, Mariëlle E. L. Wouters, Sabina Bijlsma, Ingeborg M. Kooter
Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts
Toxicological Sciences
Anita R. Iskandar, Yang Xiang, Stefan Frentzel, Marja Talikka, Patrice Leroy, Diana Kuehn, Emmanuel Guedj, Florian Martin, Carole Mathis, Nikolai V. Ivanov, Manuel C. Peitsch, Julia Hoeng
pseudomonas aeruginosaepithelial cellscytokinesgene expressionrespiratory infectionscystic fibrosisinflammationtranscription factors
Normal and Cystic Fibrosis Human Bronchial Epithelial Cells Infected with Pseudomonas aeruginosa Exhibit Distinct Gene Activation Patterns
PLOS ONE
Viviane Balloy, Hugo Varet, Marie-Agnès Dillies, Caroline Proux, Bernd Jagla, Jean-Yves Coppée, Olivier Tabary, Harriet Corvol, Michel Chignard, Loïc Guillot
immunohistochemistrybiopsyprostaglandin dexpressionasthma
D prostanoid receptor 2 (chemoattractant receptor–homologous molecule expressed on TH2 cells) protein expression in asthmatic patients and its effects on bronchial epithelial cells
Journal of Allergy and Clinical Immunology
Sally E. Stinson, Yassine Amrani, Christopher E. Brightling
infectioninflammation
Étude comparative du transcriptome de cellules épithéliales bronchiques, issues de sujets sains ou mucoviscidosiques, infectées par Pseudomonas aeruginosa
Revue des Maladies Respiratoires
V. Balloy, S. Boudaya, J. Y. Coppee, M. A. Dillies, H. Varet, C. Proux, H. Corvol, M. Chignard, L. Guillot
science / life sciences / cell biologymedical / researchmedical / toxicology
Toxicogenomics-Based Cellular Models: Alternatives to Animal Testing for Safety Assessment
Jos Kleinjans