MucilAir™ Pool nasal

MucilAir™-Pool nasal is an in vitro tissue model reconstituted with a mix of nasal cells from 14 different healthy human donors. This mix of cells is used to reconstitute an upper airway epithelium cultured at the air liquid interface (ALI). It is a powerful and predictive model for in vitro research and tests.
Being an upper airways model, MucilAir™-Pool nasal tissue is mainly composed of the following cell types:

• Basal cells (progenitor cells)
• Goblet cells (mucus producing cells)
• Ciliated cells (with active cilia)

Using a pool of donors have remarkable advantages:

• The individual donor response is averaged in one single epithelium.
• Experiments involving different donors are therefore less necessary
• Large batches of primary cells allows long term availabilities of the stocks (compared to stocks of monodonor)
• MucilAir™-Pool nasal is produced routinely at Epithelix, allowing fast delivery after ordering!

Since 2012 we produce MucilAir™-Pool nasal with high standards of quality and reproducibility. The tissue production is GIVIMP certified since 2023.

A large panel of nasal healthy donors are individually tested for their proliferation and differentiation capacities. A narrowed selection of 14 different donor candidates having similar characteristics is selected to constitute the pool. Functional QC finally validates the batch of donors.

To ensure high predictability, MucilAir™-Pool nasal is solely reconstituted using low passage human primary cells. The primary cells are isolated from human biological samples, under ethical approval and donor consent. Each batch of tissue is delivered with a certificate of analysis (COA) with donor information and quality control (QC) results.

Our models mimic the same characteristics of in vivo tissues than MucilAir™.

We handle all the production and QC process to deliver MucilAir™-Pool nasal ready-to-use at your lab. No fancy equipment of cell culture skills are required for its maintenance.

Once received, transfer the tissues in fresh medium and put it in the incubator. Then change the medium twice a week, occasionally perform a mucus wash. That’s it.

MucilAir-culture medium, dedicated, chemically defined and serum-free culture medium ensures a stable composition from batch to batch.

We ship routinely our tissues to Europe, America and Asia. Our packaging method allows to deliver safely the tissues to these locations.

We can evaluate with you the delivery to your place.

More than +800 scientific publications using Epithelix tissues.

Check out our publication page!