Publications
A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism
PLOS Pathogens (Jan. 2018)
Tseligka, Eirini D.; Sobo, Komla; Stoppini, Luc; Cagno, Valeria; Abdul, Fabien; Piuz, Isabelle; Meylan, Pascal; Huang, Song; Constant, Samuel; Tapparel, Caroline
Polarized Entry of Human Parechoviruses in the Airway Epithelium
Frontiers in Cellular and Infection Microbiology (Aug. 2018)
Karelehto, Eveliina; Cristella, Cosimo; Yu, Xiao; Sridhar, Adithya; Hulsdouw, Rens; de Haan, Karen; van Eijk, Hetty; Koekkoek, Sylvie; Pajkrt, Dasja; de Jong, Menno D.; Wolthers, Katja C.
Viral chimeras decrypt the role of enterovirus capsid proteins in viral tropism, acid sensitivity and optimal growth temperature
PLOS Pathogens (Jan. 2018)
Royston, Léna; Essaidi-Laziosi, Manel; Pérez-Rodríguez, Francisco J.; Piuz, Isabelle; Geiser, Johan; Krause, Karl-Heinz; Huang, Song; Constant, Samuel; Kaiser, Laurent; Garcin, Dominique; Tapparel, Caroline
Differential Gene Expression Using RNA Sequencing Profiling in a Reconstituted Airway Epithelium Exposed to Conventional Cigarette Smoke or Electronic Cigarette Aerosols
Applied In Vitro Toxicology (Mar. 2017)
Banerjee, Anisha; Haswell, Linsey E.; Baxter, Andrew; Parmar, Aleesha; Azzopardi, David; Corke, Sarah; Thorne, David; Adamson, Jason; Mushonganono, Jessica; Gaca, Marianna D.; Minet, Emmanuel
Reduced biological effect of e-cigarette aerosol compared to cigarette smoke evaluated in vitro using normalized nicotine dose and RNA-seq-based toxicogenomics
Scientific Reports (Apr. 2017)
Haswell, Linsey E.; Baxter, Andrew; Banerjee, Anisha; Verrastro, Ivan; Mushonganono, Jessica; Adamson, Jason; Thorne, David; Gaça, Marianna; Minet, Emmanuel
In Vitro Systems Toxicology assessment of acute exposure of an aerosol from a candidate modified-risk tobacco product on organotypic human small airways tissue culture
The FASEB Journal (Jan. 2017)
Martinez, Yannick; Iskandar, Anita; Leroy, Patrice; Martin, Florian; Sewer, Alain; Majeed, Shoaib; Trivedi, Keyur; Guedj, Emmanuel; Torres, Laura Ortega; Mathis, Carole; Frentzel, Stefan; Ivanov, Nikolai; Peitsch, Manuel; Hoeng, Julia
Accurate and reproducible dispensing of patterned picoliter quantities of tobacco extract onto apical surfaces of human 3D reconstructed airway tissues
Toxicology Letters (Oct. 2017)
Behrsing, Holger; Hilger, Norah; Huang, Song; Constant, Samuel
Factors of concern in a human 3D cellular airway model exposed to aerosols of nanoparticles
Toxicology in Vitro (Oct. 2017)
Kooter, Ingeborg M.; Gröllers-Mulderij, Mariska; Duistermaat, Evert; Kuper, Frieke; Schoen, Eric D.
Establishment and characterization of an <i>in vitro</i> human small airway model (SmallAir™)
European Journal of Pharmaceutics and Biopharmaceutics (Sep. 2017)
Huang, Song; Boda, Bernadett; Vernaz, Jimmy; Ferreira, Emilie; Wiszniewski, Ludovic; Constant, Samuel
Development of Combining of Human Bronchial Mucosa Models with XposeALI® for Exposure of Air Pollution Nanoparticles
PLOS ONE (Jan. 2017)
Ji, Jie; Hedelin, Anna; Malmlöf, Maria; Kessler, Vadim; Seisenbaeva, Gulaim; Gerde, Per; Palmberg, Lena