Publications
donor variabilitybronchial culturesmall airway cultureorganotypiclung toxicology
Comparison of the basic morphology and function of 3D lung epithelial cultures derived from several donors
Current Research in Toxicology
David Bovard, Albert Giralt, Keyur Trivedi, Laurent Neau, Petros Kanellos, Anita Iskandar, Athanasios Kondylis, Karsta Luettich, Stefan Frentzel, Julia Hoeng, Manuel C. Peitsch
Evaluation of nafamostat mesylate safety and inhibition of SARS-CoV-2 replication using a 3-dimensional human airway epithelia model
bioRxiv
D. Lynn Kirkpatrick, Jeffrey Millard
pseudomonas aeruginosatuberculosiscystic fibrosismycobacterium tuberculosistransepithelial electrical resistance (teer)air-liquid interface (ali)biofilmair-blood barrierdeposition
Disease Models: Lung Models for Testing Drugs Against Inflammation and Infection
Patrick Carius, Justus C. Horstmann, Cristiane de Souza Carvalho-Wodarz, Claus-Michael Lehr
A novel fibroblast reporter cell line for in vitro studies of pulmonary fibrosis
Frontiers in Physiology
Julia Nemeth, Annika Schundner, Karsten Quast, Manfred Frick
SARS-CoV-2 infection damages airway motile cilia and impairs mucociliary clearance
bioRxiv
Rémy Robinot, Mathieu Hubert, Guilherme Dias de Melo, Françoise Lazarini, Timothée Bruel, Nikaïa Smith, Sylvain Levallois, Florence Larrous, Julien Fernandes, Stacy Gellenoncourt, Stéphane Rigaud, Olivier Gorgette, Catherine Thouvenot, Céline Trébeau, Adeline Mallet, Guillaume Duménil, Samy Gobaa, Raphaël Etournay, Pierre-Marie Lledo, Marc Lecuit, Hervé Bourhy, Darragh Duffy, Vincent Michel, Olivier Schwartz, Lisa A. Chakrabarti
Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients
Nature Communications
S. G. P. Funnell, W. E. Dowling, C. Muñoz-Fontela, P.-S. Gsell, D. E. Ingber, G. A. Hamilton, L. Delang, J. Rocha-Pereira, S. Kaptein, K. H. Dallmeier, J. Neyts, K. Rosenke, E. de Wit, H. Feldmann, P. Maisonnasse, R. Le Grand, M. B. Frieman, C. M. Coleman
Active mucus–cilia hydrodynamic coupling drives self-organization of human bronchial epithelium
Nature Physics
Etienne Loiseau, Simon Gsell, Aude Nommick, Charline Jomard, Delphine Gras, Pascal Chanez, Umberto D’Ortona, Laurent Kodjabachian, Julien Favier, Annie Viallat
Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates
Nature
Pauline Maisonnasse, Jérémie Guedj, Vanessa Contreras, Sylvie Behillil, Caroline Solas, Romain Marlin, Thibaut Naninck, Andres Pizzorno, Julien Lemaitre, Antonio Gonçalves, Nidhal Kahlaoui, Olivier Terrier, Raphael Ho Tsong Fang, Vincent Enouf, Nathalie Dereuddre-Bosquet, Angela Brisebarre, Franck Touret, Catherine Chapon, Bruno Hoen, Bruno Lina, Manuel Rosa Calatrava, Sylvie van der Werf, Xavier de Lamballerie, Roger Le Grand
Quantifying Epithelial Plasticity as a Platform to Reverse Epithelial Injury
bioRxiv
Kristine Nishida, Baishakhi Ghosh, Lakshmana Chandrala, Saborny Mahmud, Si Chen, Atulya Aman Khosla, Joseph Katz, Venkataramana K. Sidhaye
t-cell receptormage-a4affinity-enhancedpreclinical screeningadoptive t-cell therapy
Preclinical evaluation of an affinity-enhanced MAGE-A4-specific T-cell receptor for adoptive T-cell therapy
OncoImmunology
Joseph P. Sanderson, Darragh J. Crowley, Guy E. Wiedermann, Laura L. Quinn, Katherine L. Crossland, Helen M. Tunbridge, Terri V. Cornforth, Christopher S. Barnes, Tina Ahmed, Karen Howe, Manoj Saini, Rachel J. Abbott, Victoria E. Anderson, Barbara Tavano, Miguel Maroto, Andrew B. Gerry