Publications
Methylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2 Omicron variant BA.1 infection of human airway epithelial organoids
Current Research in Microbial Sciences (Jan. 2022)
Volle, Romain; Murer, Luca; Petkidis, Anthony; Andriasyan, Vardan; Savi, Alessandro; Bircher, Cornelia; Meili, Nicole; Fischer, Lucy; Sequeira, Daniela Policarpo; Mark, Daniela Katharina; Gomez-Gonzalez, Alfonso; Greber, Urs F.
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2
Nature Cell Biology (Jan. 2022)
Samelson, Avi J.; Tran, Quang Dinh; Robinot, Rémy; Carrau, Lucia; Rezelj, Veronica V.; Kain, Alice Mac; Chen, Merissa; Ramadoss, Gokul N.; Guo, Xiaoyan; Lim, Shion A.; Lui, Irene; Nuñez, James K.; Rockwood, Sarah J.; Wang, Jianhui; Liu, Na; Carlson-Stevermer, Jared; Oki, Jennifer; Maures, Travis; Holden, Kevin; Weissman, Jonathan S.; Wells, James A.; Conklin, Bruce R.; TenOever, Benjamin R.; Chakrabarti, Lisa A.; Vignuzzi, Marco; Tian, Ruilin; Kampmann, Martin
In vitro tools for orally inhaled drug products—state of the art for their application in pharmaceutical research and industry and regulatory challenges
In vitro models (Feb. 2022)
Metz, Julia Katharina; Hittinger, Marius; Lehr, Claus-Michael
Desloratadine, an FDA-approved cationic amphiphilic drug, inhibits SARS-CoV-2 infection in cell culture and primary human nasal epithelial cells by blocking viral entry
Scientific Reports (Dec. 2022)
Morin-Dewaele, Margot; Bartier, Sophie; Berry, François; Brillet, Rozenn; López-Molina, Dennis Salomón; Nguyễn, Công Trung; Maille, Pascale; Sereno, Kevin; Nevers, Quentin; Softic, Laurent; Vaugeois, Jean-Marie; Louis, Bruno; Bequignon, Emilie; Bruscella, Patrice; Coste, André; Pawlotsky, Jean-Michel; Jamain, Stéphane; Ahmed-Belkacem, Abdelhakim
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Nature Microbiology (Aug. 2022)
Willett, Brian J.; Grove, Joe; MacLean, Oscar A.; Wilkie, Craig; De Lorenzo, Giuditta; Furnon, Wilhelm; Cantoni, Diego; Scott, Sam; Logan, Nicola; Ashraf, Shirin; Manali, Maria; Szemiel, Agnieszka; Cowton, Vanessa; Vink, Elen; Harvey, William T.; Davis, Chris; Asamaphan, Patawee; Smollett, Katherine; Tong, Lily; Orton, Richard; Hughes, Joseph; Holland, Poppy; Silva, Vanessa; Pascall, David J.; Puxty, Kathryn; da Silva Filipe, Ana; Yebra, Gonzalo; Shaaban, Sharif; Holden, Matthew T. G.; Pinto, Rute Maria; Gunson, Rory; Templeton, Kate; Murcia, Pablo R.; Patel, Arvind H.; Klenerman, Paul; Dunachie, Susanna; Haughney, John; Robertson, David L.; Palmarini, Massimo; Ray, Surajit; Thomson, Emma C.
Immunomodulation de la sensibilité néonatale au Virus Respiratoire Syncytial par des bactéries primo-colonisatrices du poumon
Revue des Maladies Respiratoires (Feb. 2022)
Marquant, Q.; Chottin, C.; Saint-Criq, V.; Laubreton, D.; Drajac, C.; Bouguyon, E.; Remot, A.; Riffault, S.; Thomas, M.; Descamps, D.
Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses
Cell Chemical Biology (May. 2022)
Napolitano, Valeria; Dabrowska, Agnieszka; Schorpp, Kenji; Mourão, André; Barreto-Duran, Emilia; Benedyk, Malgorzata; Botwina, Pawel; Brandner, Stefanie; Bostock, Mark; Chykunova, Yuliya; Czarna, Anna; Dubin, Grzegorz; Fröhlich, Tony; Hölscher, Michael; Jedrysik, Malwina; Matsuda, Alex; Owczarek, Katarzyna; Pachota, Magdalena; Plettenburg, Oliver; Potempa, Jan; Rothenaigner, Ina; Schlauderer, Florian; Slysz, Klaudia; Szczepanski, Artur; Mohn, Kristin Greve-Isdahl; Blomberg, Bjorn; Sattler, Michael; Hadian, Kamyar; Popowicz, Grzegorz Maria; Pyrc, Krzysztof
Liposomal amikacin and Mycobacterium abscessus: intimate interactions inside eukaryotic cells
Journal of Antimicrobial Chemotherapy (Dec. 2022)
Le Moigne, Vincent; Blouquit-Laye, Sabine; Desquesnes, Aurore; Girard-Misguich, Fabienne; Herrmann, Jean-Louis
Geneticin shows selective antiviral activity against SARS-CoV-2 by interfering with programmed −1 ribosomal frameshifting
Antiviral Research (Dec. 2022)
Varricchio, Carmine; Mathez, Gregory; Pillonel, Trestan; Bertelli, Claire; Kaiser, Laurent; Tapparel, Caroline; Brancale, Andrea; Cagno, Valeria
A Photoactivable Natural Product with Broad Antiviral Activity against Enveloped Viruses, Including Highly Pathogenic Coronaviruses
Antimicrobial Agents and Chemotherapy (Feb. 2022)
Meunier, Thomas; Desmarets, Lowiese; Bordage, Simon; Bamba, Moussa; Hervouet, Kévin; Rouillé, Yves; François, Nathan; Decossas, Marion; Sencio, Valentin; Trottein, François; Tra Bi, Fézan Honora; Lambert, Olivier; Dubuisson, Jean; Belouzard, Sandrine; Sahpaz, Sevser; Séron, Karin