Publications
Enhancement of chloride transport via Ca2+ mobilization in airway epithelial cells by DS-1039, a novel selective GPR39 agonist
European Journal of Pharmacology (Nov. 2025)
Muneoka, Satoshi; Inomata, Norio; Enomoto, Kei; Nakai, Daisuke; Haruyama, Munetada; Hama, Yasuhiro; Kanki, Satomi; Maeda, Yuko; Terashima, Hideki; Egashira, Shiori; Kamei, Reiko; Tomimori, Yoshiaki
Optimized intranasal delivery of segesterone acetate progestin to the brain using nanoemulsions and microemulsions
Drug Delivery and Translational Research (Dec. 2025)
Peres, Carina; Meirinho, Sara; Ferreira da Silva, Samille; Maocha, Izamara; Chiangalala, Anabela; Alves Ferreira, Susana; Rodrigues, Márcio; Zhang, Shimin; Kumar, Narender; Sitruk-Ware, Regine; Caetano Oliveira, Rui; Gaspar, Carlos; Palmeira-de-Oliveira, Ana; Palmeira-de-Oliveira, Rita; Alves, Gilberto; Baltazar, Graça; Santos, Adriana O.
Discovery of the Clinical Candidate S-892216: A Second-Generation of SARS-CoV-2 3CL Protease Inhibitor for Treating COVID-19
Journal of Medicinal Chemistry (Oct. 2025)
Unoh, Yuto; Hirai, Keiichiro; Uehara, Shota; Kawashima, Sho; Nobori, Haruaki; Sato, Jun; Shibayama, Hiromitsu; Hori, Akihiro; Nakahara, Kenji; Kurahashi, Kana; Takamatsu, Masayuki; Yamamoto, Shiho; Zhang, Qianhui; Tanimura, Miki; Dodo, Reiko; Maruyama, Yuki; Sawa, Hirofumi; Watari, Ryosuke; Miyano, Tetsuya; Kato, Teruhisa; Sato, Takafumi; Tachibana, Yuki
Evolutionary rewiring of host metabolism and interferon signalling by SARS-CoV-2 variants
nan (Nov. 2025)
Somji, Riaz-Ali; Brown, Jonathan C.; Rowles-Khalid, Shahid; Abdullahi, Tukur; Luo, Dongsheng; Barthel, Natalie; Mülleder, Michael; Ralser, Markus; Barclay, Wendy S.; Rallis, Charalampos; Giotis, Efstathios S.
Molecular basis for the activation of outer dynein arms in cilia
Nature Structural & Molecular Biology (Dec. 2025)
Issa, Karim Housseini B.; Ren, Muyang; Burnet, Bradley; Lu, Hao; Melia, Charlotte; Heesom, Kate; Roberts, Anthony J.; Roy, Sudipto; Mali, Girish R.
A combinatorial and computational Tandem approach towards a universal therapeutics against ACE2-mediated coronavirus infections
iScience (Jun. 2025)
Lee, Chia Yin; Huang, Ching-Wen; Falco, Louis De; Minhat, Rabiatul Adawiyah; Traversier, Aurélien; Wang, Bei; Salleh, Siti Nazihah Mohd; Ngoh, Eve Zi Xian; Huang, Yuling; Kim, Jenna; Tay, Matthew Zirui; Rosa-Calatrava, Manuel; Pizzorno, Andrés; Huber, Roland G.; Wang, Cheng-I.
Toxicological Effects of E-Cigarettes on Cells, Animals, and Humans and Mechanisms of Toxicity
E-Cigarettes: Risks, Research and Challenges (Jan. 2025)
Kamaruzaman, Nur Azzalia; Harun, Norsyifa; Mohideen, Mazlin
Host-targeted repurposed diltiazem enhances the antiviral activity of direct acting antivirals against Influenza A virus and SARS-CoV-2
Antiviral Research (May. 2025)
Padey, Blandine; Droillard, Clément; Dulière, Victoria; Fouret, Julien; Lamballerie, Claire Nicolas de; Milesi, Cédrine; Laurent, Emilie; Brun, Pauline; Traversier, Aurélien; Julien, Thomas; Terrier, Olivier; Rosa-Calatrava, Manuel; Pizzorno, Andrés
Best friends or biggest enemies: Differential outcomes of viral co-infections with highly pathogenic avian influenza A(H5N6) and SARS-CoV-2 in mammalian in vitro systems
nan (Oct. 2025)
Richardson, Samuel; Boodhoo, Nitish; Bhat, Sushant; Wells, Joanna; Hawes, Philippa C.; Shelton, Holly; Bialy, Dagmara
Investigating Bacterial Invasion of Highly Differentiated Human Bronchial Epithelial Cell Barriers
Dynamics of Bacteria-Mucus Interactions (Jan. 2025)
Parks, Hannah J.; Valvano, Miguel A.