Publications
caco-2calu-3apparent permeability coefficientthree-dimensional mucociliary tissue model systemnasal drug absorptionmdck
Comparison of Various Cell Lines and Three-Dimensional Mucociliary Tissue Model Systems to Estimate Drug Permeability Using an In Vitro Transport Study to Predict Nasal Drug Absorption in Rats
Pharmaceutics
Tomoyuki Furubayashi, Daisuke Inoue, Noriko Nishiyama, Akiko Tanaka, Reiko Yutani, Shunsuke Kimura, Hidemasa Katsumi, Akira Yamamoto, Toshiyasu Sakane
piezo-1purinergic signalingmechanobiologylung
Mechanical stretch activates piezo1 in caveolae of alveolar type I cells to trigger ATP release and paracrine stimulation of surfactant secretion from alveolar type II cells
The FASEB Journal
Kathrin Diem, Michael Fauler, Giorgio Fois, Andreas Hellmann, Natalie Winokurow, Stefan Schumacher, Christine Kranz, Manfred Frick
polymorphismgene expressionasthmagenotyping
Association of circadian clock TIMELESS variants and expression with asthma risk in children
The Clinical Respiratory Journal
Wojciech Langwinski, Paulina Sobkowiak, Beata Narozna, Irena Wojsyk‐Banaszak, Monika Dmitrzak‐Węglarz, Zuzanna Stachowiak, Joanna Nowakowska, Anna Bręborowicz, Aleksandra Szczepankiewicz
Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies
Scientific Reports
Katharina Schimek, Stefan Frentzel, Karsta Luettich, David Bovard, Isabel Rütschle, Laura Boden, Felix Rambo, Hendrik Erfurth, Eva-Maria Dehne, Annika Winter, Uwe Marx, Julia Hoeng
exposure cessationexposure switchingvapor productrepeated exposureorganotypic three-dimensional cultures
In vitro long-term repeated exposure and exposure switching of a novel tobacco vapor product in a human organotypic culture of bronchial epithelial cells
Journal of Applied Toxicology
Shigeaki Ito, Kazushi Matsumura, Kanae Ishimori, Shinkichi Ishikawa
I Nuovi Approcci Metodologici (NAM) per la ricerca biomedica
O. S. A. Admin
organoid3d bioprintingprimary cellorganotypic cultureimmortal cell lineinduced pluripotent stem cellair–liquid interfacenanopatterned substrate
Chapter 2 - Cell sources and methods for producing organotypic in vitro human tissue models
Organ-on-a-chip
Patrick J. Hayden
micronucleus testreconstructed human skincomet assayliver spheroidsdna damagegenotoxicity testing3d airway models
Use of in vitro 3D tissue models in genotoxicity testing: Strategic fit, validation status and way forward. Report of the working group from the 7th International Workshop on Genotoxicity Testing (IWGT)
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Stefan Pfuhler, Jan van Benthem, Rodger Curren, Shareen H. Doak, Maria Dusinska, Makoto Hayashi, Robert H. Heflich, Darren Kidd, David Kirkland, Yang Luan, Gladys Ouedraogo, Kerstin Reisinger, Toshio Sofuni, Frédérique van Acker, Ying Yang, Raffaella Corvi
Effect of sub-chronic exposure to cigarette smoke, electronic cigarette and waterpipe on human lung epithelial barrier function
BMC Pulmonary Medicine
Baishakhi Ghosh, Hermes Reyes-Caballero, Sevcan Gül Akgün-Ölmez, Kristine Nishida, Lakshmana Chandrala, Lena Smirnova, Shyam Biswal, Venkataramana K. Sidhaye
Corrigendum to “A single application of the epithelial sodium channel inhibitor BI 1265162 significantly improves water transport and mucociliary clearance of cystic fibrosis epithelial tissue, alone or combined with lumacaftor/ivacaftor or isoproterenol” Journal of Cystic Fibrosis 18 S1 (2019) S41/ePS1.07
Journal of Cystic Fibrosis
P. Nickolaus, P. Iacono, S. Constant